Names & Taxonomy

Uniprot ID:
Q9H598
Entry Name:
VIAAT_HUMAN
Status:
reviewed
Protein Names:
Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) (hVIAAT)
Gene Names:
SLC32A1 VGAT VIAAT
Gene Names Primary:
SLC32A1
Organism:
Homo sapiens (Human)

Structure

Length:
525
Sequence:
MATLLRSKLSNVATSVSNKSQAKMSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQGLQMDILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPLPPSGSKDQVGGGGEFGGHDKPKITAWEAGWNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cytoplasmic vesicle membrane

Function

Function:
Involved in the uptake of GABA and glycine into the synaptic vesicles.
Cross Reference Drug Bank:
DB00145
Gene Ontology Go:
cell tip
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
cone cell pedicle
dendrite
dendrite terminus
inhibitory synapse
integral component of membrane
neuron projection
neuron projection terminus
plasma membrane
presynaptic active zone
synaptic vesicle membrane
amino acid transmembrane transporter activity
gamma-aminobutyric acid:proton symporter activity
glycine transmembrane transporter activity
aging
amino acid transmembrane transport
hippocampus development
ion transport
neurotransmitter secretion
synaptic transmission
transmembrane transport
Gene Ontology Biological Process:
aging
amino acid transmembrane transport
hippocampus development
ion transport
neurotransmitter secretion
synaptic transmission
transmembrane transport
Gene Ontology Molecular Function:
amino acid transmembrane transporter activity
gamma-aminobutyric acid:proton symporter activity
glycine transmembrane transporter activity
Gene Ontology Cellular Component:
cell tip
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
cone cell pedicle
dendrite
dendrite terminus
inhibitory synapse
integral component of membrane
neuron projection
neuron projection terminus
plasma membrane
presynaptic active zone
synaptic vesicle membrane
Keywords:
Complete proteome
Cytoplasmic vesicle
Glycoprotein
Membrane
Neurotransmitter transport
Nitration
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
12031963 14702039 11780052 15489334 12115694