Names & Taxonomy
- Uniprot ID:
- Q9H1V8
- Entry Name:
- S6A17_HUMAN
- Status:
- reviewed
- Protein Names:
- Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17)
- Gene Names:
- SLC6A17 NTT4
- Gene Names Primary:
- SLC6A17
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 727
- Sequence:
- MPKNSKVTQREHSSEHVTESVADLLALEEPVDYKQSVLNVAGEAGGKQKAVEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPVVRNGSVAVVEAECEKSSATTYFWYREALDISDSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTNVLSRDLIPPHVNFSHLTTKDYMEMYNVIMTVKEDQFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFLVGLLFVQRSGNYFVTMFDDYSATLPLTLIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVTPPGYSAWIKEEAAERYLYFPNWAMALLITLIVVATLPIPVVFVLRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLETSGNPNGRYGSGYLLASTPESEL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Function
- Function:
- Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity).
- Gene Ontology Go:
- cell junction
integral component of plasma membrane
synaptic vesicle
synaptic vesicle membrane
amino acid transmembrane transporter activity
neurotransmitter:sodium symporter activity
alanine transport
amino acid transmembrane transport
brain development
glycine transport
leucine transport
neutral amino acid transport
proline transport - Gene Ontology Biological Process:
- alanine transport
amino acid transmembrane transport
brain development
glycine transport
leucine transport
neutral amino acid transport
proline transport - Gene Ontology Molecular Function:
- amino acid transmembrane transporter activity
neurotransmitter:sodium symporter activity - Gene Ontology Cellular Component:
- cell junction
integral component of plasma membrane
synaptic vesicle
synaptic vesicle membrane - Keywords:
- Cell junction
Complete proteome
Cytoplasmic vesicle
Disease mutation
Glycoprotein
Membrane
Mental retardation
Neurotransmitter transport
Phosphoprotein
Polymorphism
Reference proteome
Symport
Synapse
Transmembrane
Transmembrane helix
Transport