Names & Taxonomy
- Uniprot ID:
- Q9BZW2
- Entry Name:
- S13A1_HUMAN
- Status:
- reviewed
- Protein Names:
- Solute carrier family 13 member 1 (Renal sodium/sulfate cotransporter) (Na(+)/sulfate cotransporter) (hNaSi-1)
- Gene Names:
- SLC13A1 NAS1 NASI1
- Gene Names Primary:
- SLC13A1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 595
- Sequence:
- MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLTCLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane; Multi-pass membrane protein.
Function
- Function:
- Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney.
- Cross Reference Drug Bank:
- DB00139
- Gene Ontology Go:
- integral component of plasma membrane
plasma membrane
sodium:sulfate symporter activity
sodium ion transmembrane transport
sulfate transport
transmembrane transport - Gene Ontology Biological Process:
- sodium ion transmembrane transport
sulfate transport
transmembrane transport - Gene Ontology Molecular Function:
- sodium:sulfate symporter activity
- Gene Ontology Cellular Component:
- integral component of plasma membrane
plasma membrane - Keywords:
- Complete proteome
Glycoprotein
Ion transport
Membrane
Polymorphism
Reference proteome
Sodium
Sodium transport
Sulfate transport
Symport
Transmembrane
Transmembrane helix
Transport