Names & Taxonomy

Uniprot ID:
Q9BXJ3
Entry Name:
C1QT4_HUMAN
Status:
reviewed
Protein Names:
Complement C1q tumor necrosis factor-related protein 4
Gene Names:
C1QTNF4 CTRP4
Gene Names Primary:
C1QTNF4
Organism:
Homo sapiens (Human)

Structure

Length:
329
Sequence:
MLPLLLGLLGPAACWALGPTPGPGSSELRSAFSAARTTPLEGTSEMAVTFDKVYVNIGGDFDVATGQFRCRVPGAYFFSFTAGKAPHKSLSVMLVRNRDEVQALAFDEQRRPGARRAASQSAMLQLDYGDTVWLRLHGAPQYALGAPGATFSGYLVYADADADAPARGPPAPPEPRSAFSAARTRSLVGSDAGPGPRHQPLAFDTEFVNIGGDFDAAAGVFRCRLPGAYFFSFTLGKLPRKTLSVKLMKNRDEVQAMIYDDGASRRREMQSQSVMLALRRGDAVWLLSHDHDGYGAYSNHGKYITFSGFLVYPDLAPAAPPGLGASELL
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Secreted

Function

Function:
May act as a pro-inflammatory cytokine, that induces the activation of NF-kappa-B signaling pathway and up-regulates IL6 production.
Gene Ontology Go:
extracellular space
Gene Ontology Cellular Component:
extracellular space
Keywords:
Complete proteome
Cytokine
Direct protein sequencing
Reference proteome
Repeat
Secreted
Signal

Publication

PubMed ID:
15489334 21658842