Names & Taxonomy

Uniprot ID:
Q9BV28
Entry Name:
Q9BV28_HUMAN
Status:
unreviewed
Protein Names:
TUBB3 protein (Fragment)
Gene Names:
TUBB3
Gene Names Primary:
TUBB3
Organism:
Homo sapiens (Human)

Structure

Length:
406
Sequence:
ERISVYYNEASSHKYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDEEESEAQGPK

Function

Function:
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Gene Ontology Go:
microtubule
GTP binding
GTPase activity
structural constituent of cytoskeleton
microtubule-based process
Gene Ontology Biological Process:
microtubule-based process
Gene Ontology Molecular Function:
GTPase activity
GTP binding
structural constituent of cytoskeleton
Gene Ontology Cellular Component:
microtubule
Keywords:
Coiled coil
GTP-binding
Microtubule
Nucleotide-binding

Publication

PubMed ID:
15489334