Names & Taxonomy
- Uniprot ID:
- A2RUS0
- Entry Name:
- A2RUS0_HUMAN
- Status:
- unreviewed
- Protein Names:
- Adrenergic, alpha-2B-, receptor (Alpha-2B adrenergic receptor) (HCG37297)
- Gene Names:
- ADRA2B hCG_37297
- Gene Names Orf:
- hCG_37297
- Gene Names Primary:
- ADRA2B
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 450
- Sequence:
- MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEEEEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRRAQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRILCRPWTQTAW
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Gene Ontology Go:
- integral component of membrane
plasma membrane
alpha2-adrenergic receptor activity
activation of MAPK activity
female pregnancy
platelet activation
positive regulation of blood pressure
positive regulation of uterine smooth muscle contraction
regulation of vascular smooth muscle contraction - Gene Ontology Biological Process:
- activation of MAPK activity
female pregnancy
platelet activation
positive regulation of blood pressure
positive regulation of uterine smooth muscle contraction
regulation of vascular smooth muscle contraction - Gene Ontology Molecular Function:
- alpha2-adrenergic receptor activity
- Gene Ontology Cellular Component:
- integral component of membrane
plasma membrane - Keywords:
- Cell membrane
Complete proteome
G-protein coupled receptor
Membrane
Proteomics identification
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix