Names & Taxonomy
- Uniprot ID:
- Q96EY8
- Entry Name:
- MMAB_HUMAN
- Status:
- reviewed
- Protein Names:
- Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial (EC 2.5.1.17) (Cob(I)alamin adenosyltransferase) (Methylmalonic aciduria type B protein)
- Gene Names:
- MMAB
- Gene Names Primary:
- MMAB
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 250
- Sequence:
- MAVCGLGSRLGLGSRLGLRGCFGAARLLYPRFQSRGPQGVEDGDRPQPSSKTPRIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMKNDPSAESEGL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Mitochondrion
Function
- Pathway:
- Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.
- Catalytic Activity:
- ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide.; ATP + cobinamide = triphosphate + adenosylcobinamide.
- Cross Reference Drug Bank:
- DB00115 DB00200
- Gene Ontology Go:
- mitochondrial matrix
ATP binding
cob(I)yrinic acid a,c-diamide adenosyltransferase activity
cobalamin biosynthetic process
cobalamin metabolic process
small molecule metabolic process
vitamin metabolic process
water-soluble vitamin metabolic process - Gene Ontology Biological Process:
- cobalamin biosynthetic process
cobalamin metabolic process
small molecule metabolic process
vitamin metabolic process
water-soluble vitamin metabolic process - Gene Ontology Molecular Function:
- ATP binding
cob(I)yrinic acid a,c-diamide adenosyltransferase activity - Gene Ontology Cellular Component:
- mitochondrial matrix
- Keywords:
- 3D-structure
ATP-binding
Acetylation
Complete proteome
Disease mutation
Mitochondrion
Nucleotide-binding
Phosphoprotein
Polymorphism
Reference proteome
Transferase
Transit peptide