Names & Taxonomy
- Uniprot ID:
- Q8NBH6
- Entry Name:
- Q8NBH6_HUMAN
- Status:
- unreviewed
- Protein Names:
- Fibulin-1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 638
- Sequence:
- MSSWRPAVRTDTGWPLIRRTARCHMLRNPKNAGWCRSSAATASWRSCTVPRASAWPTSRTAVPRPMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVNVHIFVSEYWF
Subcellular location
- Subcellular Location:
- Secreted, extracellular space, extracellular matrix
Function
- Function:
- Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
- Gene Ontology Go:
- intracellular
proteinaceous extracellular matrix
calcium ion binding
integrin binding
peptidase activator activity
extracellular matrix organization - Gene Ontology Biological Process:
- extracellular matrix organization
- Gene Ontology Molecular Function:
- calcium ion binding
integrin binding
peptidase activator activity - Gene Ontology Cellular Component:
- intracellular
proteinaceous extracellular matrix - Keywords:
- Calcium
Disulfide bond
EGF-like domain
Extracellular matrix
Repeat
Secreted