Names & Taxonomy
- Uniprot ID:
- Q8IYC8
- Entry Name:
- Q8IYC8_HUMAN
- Status:
- unreviewed
- Protein Names:
- Beta-site APP-cleaving enzyme 1
- Gene Names:
- BACE1
- Gene Names Primary:
- BACE1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 501
- Sequence:
- MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLFSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK
Function
- Gene Ontology Go:
- integral component of membrane
aspartic-type endopeptidase activity - Gene Ontology Molecular Function:
- aspartic-type endopeptidase activity
- Gene Ontology Cellular Component:
- integral component of membrane
- Keywords:
- Aspartyl protease
Hydrolase
Membrane
Protease
Signal
Transmembrane
Transmembrane helix
Publication
- PubMed ID:
- 15489334