Names & Taxonomy
- Uniprot ID:
- Q7Z406
- Entry Name:
- MYH14_HUMAN
- Status:
- reviewed
- Protein Names:
- Myosin-14 (Myosin heavy chain 14) (Myosin heavy chain, non-muscle IIc) (Non-muscle myosin heavy chain IIc) (NMHC II-C)
- Gene Names:
- MYH14 KIAA2034 FP17425
- Gene Names Orf:
- FP17425
- Gene Names Primary:
- MYH14
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 1995
- Sequence:
- MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
- Proteomes:
- UP000005640
Function
- Function:
- Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.
- Gene Ontology Go:
- actomyosin
axon
brush border
cytosol
extracellular exosome
growth cone
membrane
myelin sheath
myosin II complex
myosin II filament
stress fiber
actin-dependent ATPase activity
ATP binding
microfilament motor activity
actin filament-based movement
actomyosin structure organization
axon guidance
ephrin receptor signaling pathway
mitochondrion morphogenesis
neuronal action potential
regulation of cell shape
sensory perception of sound
skeletal muscle contraction
skeletal muscle tissue development
small GTPase mediated signal transduction
vocalization behavior - Gene Ontology Biological Process:
- actin filament-based movement
actomyosin structure organization
axon guidance
ephrin receptor signaling pathway
mitochondrion morphogenesis
neuronal action potential
regulation of cell shape
sensory perception of sound
skeletal muscle contraction
skeletal muscle tissue development
small GTPase mediated signal transduction
vocalization behavior - Gene Ontology Molecular Function:
- actin-dependent ATPase activity
ATP binding
microfilament motor activity - Gene Ontology Cellular Component:
- actomyosin
axon
brush border
cytosol
extracellular exosome
growth cone
membrane
myelin sheath
myosin II complex
myosin II filament
stress fiber - Keywords:
- 3D-structure
ATP-binding
Acetylation
Actin-binding
Alternative splicing
Calmodulin-binding
Cell shape
Coiled coil
Complete proteome
Deafness
Direct protein sequencing
Disease mutation
Motor protein
Myosin
Neuropathy
Non-syndromic deafness
Nucleotide-binding
Phosphoprotein
Polymorphism
Reference proteome