Names & Taxonomy

Uniprot ID:
Q701N4
Entry Name:
KRA52_HUMAN
Status:
reviewed
Protein Names:
Keratin-associated protein 5-2 (Keratin-associated protein 5-8) (Keratin-associated protein 5.2) (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.2)
Gene Names:
KRTAP5-2 KAP5-8 KAP5.2 KRTAP5-8 KRTAP5.2 KRTAP5.8
Gene Names Primary:
KRTAP5-2
Organism:
Homo sapiens (Human)

Structure

Length:
177
Sequence:
MGCCGCSRGCGSGCGGCGSSCGGCGSGCGGCGSGRGGCGSGCGGCSSSCGGCGSRCYVPVCCCKPVCSWVPACSCTSCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGCSQSSCCKPCCCSSGCGSSCCQSSCCKPCCCQSSCCVPVCCQSSCCKPCCCQSNCCVPVCCQCKI
Proteomes:
UP000005640

Function

Function:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Gene Ontology Go:
keratin filament
Gene Ontology Cellular Component:
keratin filament
Keywords:
Complete proteome
Keratin
Reference proteome
Repeat

Publication

PubMed ID:
15144888 15489334