Names & Taxonomy

Uniprot ID:
Q6NVV3
Entry Name:
NIPA3_HUMAN
Status:
reviewed
Protein Names:
Magnesium transporter NIPA3 (NIPA-like protein 1) (Non-imprinted in Prader-Willi/Angelman syndrome region protein 3)
Gene Names:
NIPAL1 NIPA3 NPAL1
Gene Names Primary:
NIPAL1
Organism:
Homo sapiens (Human)

Structure

Length:
410
Sequence:
MGAQVRLPPGEPCREGYVLSLVCPNSSQAWCEITNVSQLLASPVLYTDLNYSINNLSISANVENKYSLYVGLVLAVSSSIFIGSSFILKKKGLLQLASKGFTRAGQGGHSYLKEWLWWVGLLSMGAGEAANFAAYAFAPATLVTPLGALSVLISAILSSYFLNEHLNIHGKIGCILSILGSTVMVIHAPQEEEVTSLHEMEMKLRDPGFISFAVIITVISLVLILIVAPKKGQTNILVYISICSLIGAFSVSSVKGLGIAIKELIEWKPVYKHPLVFVLLAVLVLSVTTQINYLNKALDTFNTSLVTPIYYVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIFLLHAFKNTDITWSELTSTAKKEAVSLNVNENNYVLLENLECSAPGYNDDVTLFSRTDD
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Membrane

Function

Function:
Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity).
Gene Ontology Go:
integral component of membrane
magnesium ion transmembrane transporter activity
magnesium ion transport
Gene Ontology Biological Process:
magnesium ion transport
Gene Ontology Molecular Function:
magnesium ion transmembrane transporter activity
Gene Ontology Cellular Component:
integral component of membrane
Keywords:
Complete proteome
Glycoprotein
Ion transport
Magnesium
Membrane
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
14702039 17974005 15489334