Names & Taxonomy
- Uniprot ID:
- Q6L8H2
- Entry Name:
- KRA53_HUMAN
- Status:
- reviewed
- Protein Names:
- Keratin-associated protein 5-3 (Keratin-associated protein 5-9) (Keratin-associated protein 5.3) (Keratin-associated protein 5.9) (UHS KerB-like) (Ultrahigh sulfur keratin-associated protein 5.3)
- Gene Names:
- KRTAP5-3 KAP5-9 KAP5.3 KRTAP5-9 KRTAP5.3 KRTAP5.9
- Gene Names Primary:
- KRTAP5-3
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 238
- Sequence:
- MGCSGCSGGCGSSCGGCGSSCGGCGSGYGGCGSGCCVPVCCCKPVCCCVPACSCSSCGSCGGSKGVCGSCGGCKGGCGSCGGSKGGCGSSCCVPVCCSSSCGSCGGSKGVCGFRGGSKGGCGSCGCSQCSCYKPCCCSSGCGSSCCQSSCCKPSCSQSSCCKPCCSQSSCCKPCCCSSGCGSSCCQSSCCKPCCSQSSCCKPCCCSSGCGSSCCQSSCCKPCSSQSSCCVPICCQCKI
- Proteomes:
- UP000005640
Function
- Function:
- In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
- Gene Ontology Go:
- keratin filament
- Gene Ontology Cellular Component:
- keratin filament
- Keywords:
- Complete proteome
Keratin
Polymorphism
Reference proteome
Repeat
Publication
- PubMed ID:
- 15144888