Names & Taxonomy
- Uniprot ID:
- Q5VZX0
- Entry Name:
- Q5VZX0_HUMAN
- Status:
- unreviewed
- Protein Names:
- Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2, isoform CRA_a (cDNA FLJ12746 fis, clone NT2RP2000842, highly similar to Lysophosphatidic acid receptor Edg-2) (cDNA FLJ78319, highly similar to Homo sapiens endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 (EDG2), transcript variant 2, mRNA)
- Gene Names:
- EDG2 hCG_27597
- Gene Names Orf:
- hCG_27597
- Gene Names Primary:
- EDG2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 364
- Sequence:
- MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV
Function
- Gene Ontology Go:
- cytoplasm
dendritic shaft
dendritic spine
integral component of plasma membrane
neuronal cell body
lysophosphatidic acid receptor activity
phospholipid binding
activation of MAPK activity
activation of phospholipase C activity
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
bleb assembly
cellular response to 1-oleoyl-sn-glycerol 3-phosphate
cellular response to oxygen levels
cerebellum development
corpus callosum development
myelination
negative regulation of cAMP biosynthetic process
negative regulation of neuron projection development
oligodendrocyte development
optic nerve development
positive regulation of apoptotic process
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
positive regulation of dendritic spine development
positive regulation of Rho protein signal transduction
positive regulation of smooth muscle cell chemotaxis
positive regulation of stress fiber assembly
regulation of cell shape - Gene Ontology Biological Process:
- activation of MAPK activity
activation of phospholipase C activity
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
bleb assembly
cellular response to 1-oleoyl-sn-glycerol 3-phosphate
cellular response to oxygen levels
cerebellum development
corpus callosum development
myelination
negative regulation of cAMP biosynthetic process
negative regulation of neuron projection development
oligodendrocyte development
optic nerve development
positive regulation of apoptotic process
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
positive regulation of dendritic spine development
positive regulation of Rho protein signal transduction
positive regulation of smooth muscle cell chemotaxis
positive regulation of stress fiber assembly
regulation of cell shape - Gene Ontology Molecular Function:
- lysophosphatidic acid receptor activity
phospholipid binding - Gene Ontology Cellular Component:
- cytoplasm
dendritic shaft
dendritic spine
integral component of plasma membrane
neuronal cell body - Keywords:
- G-protein coupled receptor
Membrane
Receptor
Transducer
Transmembrane
Transmembrane helix