Names & Taxonomy
- Uniprot ID:
- Q496J9
- Entry Name:
- SV2C_HUMAN
- Status:
- reviewed
- Protein Names:
- Synaptic vesicle glycoprotein 2C
- Gene Names:
- SV2C KIAA1054
- Gene Names Primary:
- SV2C
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 727
- Sequence:
- MEDSYKDRTSLMKGAKDIAREVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEEDDDDYYPAGETYNGEANDDEGSSEATEGHDEDDEIYEGEYQGIPSMNQAKDSIVSVGQPKGDEYKDRRELESERRADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIKTPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVRDNTIKLTIVWFTLSFGYYGLSVWFPDVIKPLQSDEYALLTRNVERDKYANFTINFTMENQIHTGMEYDNGRFIGVKFKSVTFKDSVFKSCTFEDVTSVNTYFKNCTFIDTVFDNTDFEPYKFIDSEFKNCSFFHNKTGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKSIPILLASTVLVCGGLVGLCLPDTRTQVLM
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Function
- Function:
- Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity).
- Gene Ontology Go:
- cell junction
integral component of membrane
plasma membrane
synaptic vesicle
synaptic vesicle membrane
transmembrane transporter activity
neurotransmitter transport - Gene Ontology Biological Process:
- neurotransmitter transport
- Gene Ontology Molecular Function:
- transmembrane transporter activity
- Gene Ontology Cellular Component:
- cell junction
integral component of membrane
plasma membrane
synaptic vesicle
synaptic vesicle membrane - Keywords:
- 3D-structure
Cell junction
Complete proteome
Cytoplasmic vesicle
Glycoprotein
Membrane
Neurotransmitter transport
Polymorphism
Reference proteome
Synapse
Transmembrane
Transmembrane helix
Transport